I think you've got to take the risks. There's no point playing it safe, because either you'll get bored or the audiences will get bored. Sometimes, you're going to make mistakes, and that's fine, but you have to take the risks. I think Pirates is one of the prime examples of that with Johnny Depp's performance, and part of the reason that people love it so much is that you watch it and go, "Gutsy, really gutsy!"
